Exposure to chemical cocktails before or after conception – The effect of timing on ovarian development

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Exposure to chemical cocktails before or after conception – The effect of timing on ovarian development☆

Exposure of female fetuses to environmental chemicals (ECs) during pregnancy results in a disturbed ovarian adult phenotype. We investigated the influence of pre- and/or post-conception exposure to low-level mixtures of ECs on the structure and function of the fetal ovine ovary. We examined ovarian morphology, expression of oocyte and granulosa cell-specific genes and proteome. Female fetuses w...

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ژورنال

عنوان ژورنال: Molecular and Cellular Endocrinology

سال: 2013

ISSN: 0303-7207

DOI: 10.1016/j.mce.2013.06.016